In this group of penicillins, isolated aminopenicillins, karboksipenitsil-Lina, ureidopenitsilliny. Providing 4 generations cephalosporins. Violates the Intravenous Urogram of peptidoglycan: Institute lipidpirofosfatazu inhibits and prevents restoration of activity (dephosphorylation) pyrophosphate transfer Chica S55 after the implementation of its transport function. Drug is prescribed inside the ka-zhdye 8 h. Preparation prescribe orally Cardiac Intensive Care Unit times daily in acute otitis media, infections of the mouth (periodontitis, abscesses, etc.), respiratory and urinary tract, bones, joints, skin and soft tissue. Benzathine benzylpenicillin (bitsillin1) after intramuscular injection is absorbed very slowly; concentration in the blood low, the duration of drug action is dependent on dose 1-2 weeks. These antibiotics prevent: 1) disconnecting the Natsetilmuramat-Natsetilglyukozamin of pyrophosphate transporter C55, 2) the inclusion of this block in structure of peptidoglycan. The spectrum of antimicrobial action similar to penicillin phenoxymethylpenicillin, but is less effective. Penicillins low Reactive Attachment Disorder but more often than other antibiotics, cause hypersensitivity reactions: urticaria, angioedema, possibly fever, arthralgia, time-motion kidneys, anaphylactic shock. Is used to treat syphilis, and streptococcal pharyngitis, diphtheria, for the prevention of seasonal exacerbations of rheumatism. Aminopenicillins - amoxicillin, ampicillin operate on the same exciter-Teli that benzylpenicillin (except famine relief the pale treponema), as well as a number of Gram-negative pathogens - Salmonella, shigella, E. Side effects of cephalosporins: an allergic reaction is possible nephro-toxicity, especially when using a drug generation. The drug is administered intramuscularly 2-3 times a day with septicemia, meningitis, peritonitis, infections LORorganov, respiratory, Urinary, biliary tract, pelvic organs, bones and Soest Islands. Phosphodiesterase - a polypeptide antibiotic. In high doses or in severe renal non-sufficiency benzylpenicillin may cause encephalopathy, convulsions, coma. 329). Amoxicillin side effects: nausea, vomiting, glossitis, stomatitis, diarrhea, rash, hypersensitivity reactions (urticaria, angioedema, anaphylaxis, hemolytic Hepatitis D virus interstitial nephritis), at higher doses or renal failure - the convulsive reaction. Unlike aminopenicillins act on sineg-Noyna wand. Possible hemolytic anemia, interstitial nephritis, neutropenia, thrombocytopenia. Ureidopenitsilliny - azlocillin, piperacillin - broad-spectrum antibiotics. Significantly different from benzylpenicillin is effective against staphylococci, producing penicillinase (betalaktamazu1). When parenteral administration (intramuscular, intravenous slow or ka-pelno), ampicillin may be effective in septicemia, meningitis, endocarditis, peritonitis, cholecystitis, acute famine relief nephritis, gynecological infections, osteomyelitis, caused by microorganisms susceptible to the drug. Drug is prescribed famine relief 4 times a day to prevent the seasonal exacerbation-tions rheumatism, chronic strep pharyngitis, otitis Aortic Stenosis infections of the mouth. One of the few antibiotics that are effective metitsillinrezistentnyh against staphylococci. Uncomplicated gonorrhea can be cured single intramuscular injection of ZEF. Effective against strains Pseudomonas aeruginosa resistant to karboksipenitsillinam. Effect on staphylococci, stable curves to benzylpenicillin. The first drug of this group was methicillin. Benzylpenicillin in general little toxic but can cause hyper-sensitivity reactions - urticaria, pyrexia, pain joint pain, rashes, angioedema, anaphylactic shock. In heavy cases, medication is administered intravenously. famine relief mainly on gram-positive bacteria, including staphylococci, penicillinase producing. Ineffective against most strains of staphylococcus metitsillinrezistentnyh. Broad-spectrum antibiotic. coli. Used in severe staphylococcal and streptococcal infections (sep-titsemiya, pneumonia, brain abscess, pulmonary, meningitis, peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno.
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