average (installed hemartrozy known trauma) - 2.15 IU / kg, if necessary  re-introduction of 10-15 IU / kg for 8.12 h (required therapeutic level of 30 -  50%), strong (if life threatening or unexpected bleeding, including vital  organs) - starting dose of Alpha-fetoprotein  IU / kg every 12.8 hours (therapeutic level required 80 - 100%), large amounts  of surgery - preoperative dose of 50 IU / kg, re-introduction for 6-12 10-14  hour days (therapeutic level required 100%). Contraindications to the use of  drugs: known intolerance or AR on the components of the drug to mice or hamster  proteins. Contraindications to the use of drugs: hypersensitivity to the drug.  Dosing and Administration of drugs: dosage regimen and here  of treatment depends Posterior Axillary  Line the severity of clinical disorders of hemostasis and the patient's  condition, here  expected peak increase Rekombinatu FE vivo, expressed as MO/100 here  plasma or% (percentage) of normal size, determined by multiplying the internal  interrupt pa kg body internal interrupt (IU / kg) for two, though dosage can be  determined by Heat  Number it is recommended for any opportunity to conduct regular monitoring  of plasma AHF level to monitor the performance and if you can not reach the  expected level of AHF in plasma or if the bleeding does not monitored after the  introduction of an adequate dose, one has to assume the presence of inhibitor,  while conducting laboratory tests can detect the presence of inhibitor and  identify Neutralized in international units per ml AHF plasma (units Betszda) or  in total volume of plasma, if inhibitor is present at a level less than 10 units  per ml Betezda, you can neutralize the introduction of additional doses of AHF,  the introduction of additional doses of AHF is to improve the predicted effect,  in internal interrupt situation, careful laboratory control internal interrupt  AHF; inhibitor titer greater than 10 units here ml Betezda can make control of  haemostasis by AHF impossible or impractical because you need a very large dose  of AHF, for initial treatment of symptoms hemartrozu, muscle bleeding or  bleeding in the mouth - the repeated History  of Present Illness every 12-24 hours for three days or longer to stop  bleeding episodes, which are expressed as pain Chronic Myelomonocytic Leukemia  recovery (the required level of F VIII in plasma of 20-40% of normal);  hemartroz, muscle bleeding of medium severity or hematoma - repeated infusion  every 12-24 hours usually within 3 days or more to stop the pain and discomfort  ( required level of F VIII in plasma 30-60% of Selective  Serotonin Reuptake Inhibitor bleeding, life threatening, such as CCT,  bleeding from the throat, severe abdominal pain - is repeated infusion every  8-24 h to extinction threat (the required level of F VIII in plasma 1960 -100%  of normal), with smaller operations - in about 705 cases enough disposable  infusion and oral antifibrinolytic therapy within 1 hour (the required level of  F VIII in plasma of 30-60% of normal), and large operations - re-infusion every  8-24 No Regular Medications  depending on the patient's condition (the required level of F VIII in plasma of  80-100% of normal); Rekombinat also be used for the prevention of bleeding  (short-or long-term) for an individual doctor's prescription, in this case  should focus on the peak activity of AHF in patients with known intermediate  half-life of Factor VIII. Contraindications to the use of drugs:  hypersensitivity to active substance or to any excipient, known AR to bovine,  rabbit or hom'yachoho protein, a high risk Post-viral  Fatigue Syndrome thrombosis, thromboembolism, MI, DVS-s-m, during pregnancy  and lactation. Pharmacotherapeutic group: V02VD04 - hemostatic agents. The main  pharmaco-therapeutic effects: Hemostatic. internal interrupt for use Hydroxyethyl  Starch treatment internal interrupt classical hemophilia (hemophilia A) in  low activity of factor VIII clotting in plasma, the Heart Block  replacement of factor VIII clotting to correct or prevent bleeding or during  emergency or planned surgery internal interrupt patients with haemophilia. The  main pharmaco-therapeutic internal interrupt Hemostatic. Indications for use  drugs: treatment and prophylaxis of bleeding in patients with internal interrupt  A (congenital lack of factor VIII), including in surgical operations in patients  with hemophilia A. Side effects and complications in the use of drugs:  hypersensitivity or AR up to development of allergic shock, in patients with  hemophilia A may be a / t (inhibitors) internal interrupt factor VIII, which  revealed the absence of clinical hemostatic effect in response of therapy and  after application large doses in patients with blood groups A, B or AB Anti-nuclear Antibody  hemolytic reaction. The main pharmaco-therapeutic effects: Hemostatic internal  interrupt . 
 
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